News Release
April 24, 2001
FOR IMMEDIATE RELEASE

Contact: Megan E. Michael
(301) 405-8306

Inventions of the Year Announced,
Research and Technology
Transfer Celebrated
at the University of Maryland


COLLEGE PARK, MD . . . A novel method for producing rare carotenoids that may be vital as nutrients and as therapies for diseases such as cancer and age-related macular degeneration; an accurate and inexpensive technology that can "PinPoint" the location of all the nodes (cell phones, computers, etc.) of a wireless network and synchronize their actions; and a new platform technology that improves upon widely-used existing "breadboard tables," as platforms for fiber optic research are called, are the University of Maryland's three Inventions of the Year 2000.

William W. Destler, University of Maryland's Vice President of Research and Dean of the Graduate School, will present plaques and $500 in award money to the inventors of the winning technologies today at the 14th Annual Invention of the Year Reception held by the Office of Technology Commercialization (OTC).

Life Science Invention of the Year

Fred Khachik, an adjunct professor in Maryland's Department of Chemistry and Biochemistry, has developed a novel method to extract and purify carotenoids that are not commercially available for research to study their properties for use as nutritional supplements and as drug therapies for chronic diseases such as cancer, age-related macular degeneration and cardiovascular disease. Carotenoids--the yellow to red compounds found in plants and animals--possess antioxidant and anti-cancer properties and are valuable supplements to the human diet.

Several dietary carotenoids, such as beta-carotene, lutein, and lycopene, are commercially available in various formulations. However, anhydrolutein, alpha-cryptoxanthin, beta-cryptoxanthin and zeaxanthin, four of the 12 major dietary carotenoids found in human serum, milk, major organs and tissues, are rare in nature. Khachik's patent-pending method converts commercially available lutein (isolated from extracts of marigold flowers) into a mixture of alpha-cryptoxanthin, beta-cryptoxanthin and minor quantities of anhydrolutein in one simple step, making these rare carotenoids available for further research into their use as preventive methods or treatments for many degenerative and deadly diseases.

Other finalists in the life science category were entitled "Integrated Microfluidic System Enabling Rapid Protein Digestion, Peptide Separation and Protein Identification," developed by Cheng Lee; and "Dermal Immunization of Chickens with a Unique Plasmid DNA," developed by Robert Heckert and Subbiah Elankumaran.


Information Science Invention of the Year

Researchers at Maryland's Department of Computer Science have developed an accurate, rapid and inexpensive technology that determines the spatial layout of a wireless network of nodes. The patent-pending PinPoint Technology, developed by Ashok Agrawala, A. Shankar, Ronald Larsen and Douglas Szajda, also allows every node to determine the relative offset and drift of every other node's clock, making it possible for all of the nodes to carry out a precise synchronized action. Research results show that the PinPoint Technology can determine location to an accuracy of a few centimeters and determine clock differences to an accuracy of a nanosecond.

PinPoint Technology has significant implications for a broad range of wireless networking infrastructure applications. The rapid availability of accurate location information can greatly simplify and optimize the implementation of ad-hoc networks and sensor-based applications.

Other finalists in the information science category were entitled "A Storytelling Robot for Pediatric Rehabilitation," developed by Allison Druin, Catherine Plaisant-Schwenn and Corinna Lathan; and "Maryland Phosphorus Site Index (PSI) Software," developed by Robert Hill, Eugene Mironenko, Franklin Robbins and Chad Forgette.

Physical Science Invention of the Year

Steve Baker, a former research technician with Maryland's Department of Electrical and Computer Engineering, has developed a novel Fiber Optic Breadboard workstation that provides a scaleable environment for fiber optic research. Conventional breadboard tables have large, horizontal surfaces with patterns of threaded holes that are used to secure the necessary testing equipment, such as clamps, meters and sensors. This set-up consumes valuable workspace and often results in confusing layouts that make troubleshooting during experiments difficult.

The patent-pending breadboard developed by Baker, that is set up using simple, three-dimensional modular stacking platforms, can be mounted on top of a traditional breadboard table. This layout effectively increases the amount of available workspace. Baker's breadboard also features a pattern of threaded holes and a quick clamp system to assemble and stack the platforms without affecting its structural integrity. In addition to fiber optic research, Baker's breadboard can be used for free-space optics, remote sensing and smart structures research.

Since inventing the Fiber Optic Breadboard, Baker has formed a University of Maryland start-up company based on the technology. Optical Fiber Research Resources, Inc., of Baltimore, Md., licensed the Fiber Optic Breadboard from OTC and will be manufacturing and distributing the novel breadboard.

Other finalists in the physical science category were entitled "Wet Gas Temperature Measurement Probe," developed by Marino diMarzo and Paolo Ruffino; and "Evaporation/Condensation of Metal Clusters for the Production of III-V Semiconductor Nanocrystals by Aerotaxy," developed by Sheryl Ehrman, Yogendra Singh, Julie Rose Javier, Knut Deppert and Martin Magnusson.

The Office of Technology Commercialization (OTC) at the University of Maryland was established in 1986 to facilitate the transfer of information, life and physical science inventions developed at the university to business and industry. In the past 14 years, OTC has recorded more than 1000 technologies, secured more than 150 patents and executed more than 480 license agreements, generating more than $17 million in technology transfer income. In addition, 22 high-tech start-up companies have been formed based on technologies developed at the university.

For more information, contact Megan E. Michael
at (301) 403-2711 ext. 17.




Updated 4/2001

Office of Technology Commercialization
University of Maryland
6200 Baltimore Avenue, Suite 300
Riverdale, Maryland 20737-1054

301-403-2711 tel d301-403-2717 fax
otc@umd.edu

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